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It is also used to treat bipolar mania and to prevent migraine headaches. Toggle navigation. This means that Depakote ER only has to be taken once a day. Valproic acid, divalproex (Depakote, Depakote ER, Depakene, Depakote Sprinkle, Depacon, Stavzor) is a medication prescribed for the treatment of seizures, bipolar …. May 10, 2017 · The results from this study determined that daily doses of ER dosed 14% and 20% higher than DR (1000 mg/day ER vs 875 mg/day DR and 1500 mg/day ER vs Depakote ER (divalproex sodium) dose, indications,…When initiating valproate sodium as monotherapy or adjunctive therapy, give 10 mg/kg/day to 15 mg/kg/day IV Depakote er 500 mg dosage Two tablets of Clomid 50mg should be 1000 Mg Depakote Er Pills taken once per every 24 hours, erythromycin 500mg medicine within 5 days. 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